ENTEROAGGREGATIVE ESCHERICHIA-COLI STRAINS SECRETE A HEAT-LABILE TOXIN ANTIGENICALLY RELATED TO ESCHERICHIA-COLI HEMOLYSIN

被引：53

作者：

BALDWIN, TJ

KNUTTON, S

SELLERS, L

HERNANDEZ, HAM

AITKEN, A

WILLIAMS, PH

机构：

[1] UNIV BIRMINGHAM,INST CHILD HLTH,BIRMINGHAM B16 8ET,ENGLAND

[2] UNIV LEICESTER,DEPT GENET,LEICESTER LE1 7RH,ENGLAND

[3] NATL INST MED RES,LONDON NW7 1AA,ENGLAND

来源：

INFECTION AND IMMUNITY | 1992年 / 60卷 / 05期

基金：

英国惠康基金;

关键词：

D O I：

10.1128/IAI.60.5.2092-2095.1992

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A protein toxin of approximately 120,000 Da secreted by nonhemolytic enteroaggregative Escherichia coli strains cross-reacted in Western blots (immunoblots) with antibodies raised against the C-terminal region of E. coli hemolysin. Treatment of HEp-2 cells with enteroaggregative E. coli or culture supernatants caused elevation of intracellular calcium and stimulated calcium-dependent protein phosphorylation.

引用

页码：2092 / 2095

页数：4

共 30 条

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