POSSIBLE MECHANISM OF ENTRAPMENT OF NEURAMINIDASE-TREATED LYMPHOCYTES IN LIVER

被引：58

作者：

KOLB, H

KRIESE, A

KOLBBACHOFEN, V

KOLB, HA

机构：

[1] UNIV CONSTANCE,DEPT BIOCHEM,D-7750 CONSTANCE,FED REP GER

[2] UNIV DUSSELDORF,INST ELECTR MICROSCOPY,DEPT MED,D-4000 DUSSELDORF 1,FED REP GER

来源：

CELLULAR IMMUNOLOGY | 1978年 / 40卷 / 02期

关键词：

D O I：

10.1016/0008-8749(78)90355-6

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Neuraminidase-treated rat lymphocytes adhere strongly to rat hepatocytes in vitro. Binding between cells is due to stereo-specific interactions between a mammalian hepatic membrane lectin and galactosyl residues which are exposed on the lymphocyte surface after removal of sialic acid residues. The hepatic galactose specific lectin may play a role in the trapping of recirculating desialylated lymphocytes in the liver. © 1978.

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页码：457 / 462

页数：6

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