POSSIBLE MECHANISM OF ENTRAPMENT OF NEURAMINIDASE-TREATED LYMPHOCYTES IN LIVER

被引:58
作者
KOLB, H
KRIESE, A
KOLBBACHOFEN, V
KOLB, HA
机构
[1] UNIV CONSTANCE,DEPT BIOCHEM,D-7750 CONSTANCE,FED REP GER
[2] UNIV DUSSELDORF,INST ELECTR MICROSCOPY,DEPT MED,D-4000 DUSSELDORF 1,FED REP GER
关键词
D O I
10.1016/0008-8749(78)90355-6
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Neuraminidase-treated rat lymphocytes adhere strongly to rat hepatocytes in vitro. Binding between cells is due to stereo-specific interactions between a mammalian hepatic membrane lectin and galactosyl residues which are exposed on the lymphocyte surface after removal of sialic acid residues. The hepatic galactose specific lectin may play a role in the trapping of recirculating desialylated lymphocytes in the liver. © 1978.
引用
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页码:457 / 462
页数:6
相关论文
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