HOT-WATER EXTRACTS OF CHLORELLA-VULGARIS REDUCE OPPORTUNISTIC INFECTION WITH LISTERIA-MONOCYTOGENES IN C57BL/6 MICE INFECTED WITH LP-BM5 MURINE LEUKEMIA VIRUSES

被引：40

作者：

HASEGAWA, T

OKUDA, M

MAKINO, M

HIROMATSU, K

NOMOTO, K

YOSHIKAI, Y

机构：

[1] CHLORELLA IND CO LTD,RES LABS,CHIKUGO,FUKUOKA 833,JAPAN

[2] NATL INST HLTH,CTR AIDS RES,DEPT BLOOD PROD,SHINJUKU KU,TOKYO 162,JAPAN

[3] KYUSHU UNIV,MED INST BIOREGULAT,DEPT IMMUNOL,FUKUOKA 812,JAPAN

来源：

INTERNATIONAL JOURNAL OF IMMUNOPHARMACOLOGY | 1995年 / 17卷 / 06期

关键词：

D O I：

10.1016/0192-0561(95)00035-Z

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The bacterial elimination after infection with Listeria monocytogenes was impaired in mice with murine acquired immunodeficiency syndrome (MAIDS) by infection with LP-BM5 murine leukemia virus. Oral administration of hot water extracts of Chlorella vulgaris (CVE) restored the capacity of MAIDS mice to eliminate L. monocytogenes in association with improvement of the deteriorated immune response to L. monocytogenes. DTH response to Listeria in CVE-treated MAIDS mice was significantly higher than that of MAIDS mice after Listeria infection in association with increases in number of CD4(+)CD8(-) and CD4(-)CD8(+) alpha beta T-cells in the infected sites. CVE might be effective in the treatment of opportunistic infection in retrovirus-induced immunodeficient patients.

引用

页码：505 / 512

页数：8

共 23 条

[21] ROLE OF T-CELL DERIVED CYTOKINES IN THE DOWN-REGULATION OF IMMUNE-RESPONSES IN PARASITIC AND RETROVIRAL INFECTION [J].