NATURALLY-OCCURRING PEPTIDE ANTIGENS DERIVED FROM THE MHC CLASS-I-RESTRICTED PROCESSING PATHWAY

被引：184

作者：

ROTZSCHKE, O

FALK, K

机构：

[1] Max-Planck-Institut für Biologie, Abteilung Immungenetik, W-7400 Tübingen

来源：

IMMUNOLOGY TODAY | 1991年 / 12卷 / 12期

关键词：

D O I：

10.1016/0167-5699(91)90018-O

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The extraction of naturally-processed peptides from MHC class I glycoproteins has paved the way for a major advance in the understanding of the antigen processing pathway that ultimately induces cytotoxic T-cell responses. Here, Olaf Rotzschke and Kirsten Falk review these new developments and discuss their findings in terms of a novel hypothesis of MHC class-I-restricted processing.

引用

页码：447 / 455

页数：9

共 86 条

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