SURGICAL-TREATMENT OF INTRACTABLE SEIZURES DUE TO HYPOTHALAMIC HAMARTOMA

被引:73
作者
NISHIO, S [1 ]
MORIOKA, T [1 ]
FUKUI, M [1 ]
GOTO, Y [1 ]
机构
[1] KYUSHU UNIV,FAC MED,NEUROL INST,DEPT NEUROSURG,FUKUOKA 812,JAPAN
关键词
HYPOTHALAMIC NEOPLASMS; NEUROLOGIC MANIFESTATIONS; NEUROSURGERY; SEIZURES; ELECTROENCEPHALOGRAPHY;
D O I
10.1111/j.1528-1157.1994.tb02470.x
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
A 6.5-year-old boy developed seizures at age 2.8 years consisting of episodes of unconsciousness and laughing attacks. By age 6 years, multiple seizure types, including generalized tonic-clonic (GTC), complex partial (CPS) and akinetic seizures, and drop attacks were occurring several times daily. EEG showed multifocal epileptic discharges. Antiepileptic drugs (AEDs) did not control the seizures. With progression of the epilepsy, cognitive deterioration developed. There were no manifestations of precocious puberty. Neuroimaging disclosed a suprasellar mass in continuity with the hypothalamus, and a diagnosis of hypothalamic hamartoma was made. After surgical resection of the hamartoma, the seizures were completely alleviated, and the epileptic EEG discharges disappeared. Improvement of mental function was also noted.
引用
收藏
页码:514 / 519
页数:6
相关论文
共 23 条
[11]   FITS OF LAUGHTER (GELASTIC EPILEPSY) WITH A TUMOR OF FLOOR OF 3RD VENTRICLE - VIDEO TAPE ANALYSIS [J].
DREYER, R ;
WEHMEYER, W .
JOURNAL OF NEUROLOGY, 1977, 214 (03) :163-171
[13]  
JINNAI D, 1980, ADV EPILEPTOL, P227
[14]   POSTERIOR HYPOTHALAMIC HAMARTOMAS AND GANGLIOGLIOMAS CAUSING PRECOCIOUS PUBERTY [J].
LIST, CF ;
DOWMAN, CE ;
BAGCHI, BK ;
BEBIN, J .
NEUROLOGY, 1958, 8 (03) :164-174
[15]   GELASTIC SEIZURES TREATED BY RESECTION OF A HYPOTHALAMIC HAMARTOMA [J].
MACHADO, HR ;
HOFFMAN, HJ ;
HWANG, PA .
CHILDS NERVOUS SYSTEM, 1991, 7 (08) :462-465
[16]   HYPOTHALAMIC HAMARTOMA - REPORT OF 2 CASES [J].
NISHIO, S ;
FUJIWARA, S ;
AIKO, Y ;
TAKESHITA, I ;
FUKUI, M .
JOURNAL OF NEUROSURGERY, 1989, 70 (04) :640-645
[17]   PUBERTAS PRAECOX DUE TO HYPOTHALAMIC HAMARTOMA - REPORT OF 2 CASES SURVIVING SURGICAL REMOVAL OF TUMOUR [J].
NORTHFIELD, DW ;
RUSSELL, DS .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1967, 30 (02) :166-+
[18]  
PONSOT G, 1983, ARCH FR PEDIATR, V40, P757
[19]   HYPOTHALAMIC HAMARTOMA - REPORT OF 2 CASES [J].
SATO, M ;
USHIO, Y ;
ARITA, N ;
MOGAMI, H .
NEUROSURGERY, 1985, 16 (02) :198-206
[20]   THE EEG IN DEEP MIDLINE LESIONS [J].
SCHAUL, N ;
GLOOR, P ;
GOTMAN, J .
NEUROLOGY, 1981, 31 (02) :157-167