HIGH MOLECULAR-WEIGHT ALKALINE-PHOSPHATASE - CLINICAL-STUDY

被引:29
作者
CROFTON, PM [1 ]
ELTON, RA [1 ]
SMITH, AF [1 ]
机构
[1] UNIV EDINBURGH, MED COMP & STAT UNIT, EDINBURGH EH8 9AG, MIDLOTHIAN, SCOTLAND
关键词
D O I
10.1016/0009-8981(79)90153-0
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
High molecular weight alkaline phosphatase activities have been measured in the sera of 72 patients with a variety of forms of liver disease, 14 patients with bone disease and 8 healthy volunteers. These measurements have been compared with measurements of other indices of hepatic function in order to establish the place of this enzyme in the diagnosis of liver disease. High molecular weight alkaline phosphatase proved to be a sensitive and specific test for detecting liver disease, particularly obstructive liver disease. It was better than all the other liver function tests in distinguishing liver metastases from other hepatobiliary diseases. It may therefore prove especially useful in the early detection of liver metastases. © 1979.
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页码:263 / 275
页数:13
相关论文
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[21]  
WINKEL P, 1975, CLIN CHEM, V21, P71