A RAPID ASSAY FOR THE ENANTIOMERIC PURITY OF SECONDARY ALCOHOLS USING 4S,5R-4-METHYL,5-PHENYL-1,3,2-OXAZABOROLIDINE (EPHEDRINEBORANE)

被引：8

作者：

BROWN, JM

LEPPARD, SW

LLOYDJONES, GC

机构：

[1] Dyson Perrins Laboratory, Oxford, OX1 3QY England, South Parks Rd

来源：

TETRAHEDRON-ASYMMETRY | 1992年 / 3卷 / 02期

关键词：

D O I：

10.1016/S0957-4166(00)80205-0

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Reaction of the title compound with a series of racemic and optically enriched secondary alcohols in C7D8 solution at 20-degrees-C leads to rapid formation of the corresponding borate. The N-CH3 protons of the ephedrine moiety, and frequently other resonances, were generally resolved in the H-1 NMR spectrum. permitting an estimation of the enantiomeric purity of the alcohol.

引用

页码：261 / 266

页数：6

共 30 条

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