PSYCHOLOGICAL STRESS INCREASES SEROTONIN RELEASE IN THE RAT AMYGDALA AND PREFRONTAL CORTEX ASSESSED BY IN-VIVO MICRODIALYSIS

被引：204

作者：

KAWAHARA, H ^{[1
]}

YOSHIDA, M ^{[1
]}

YOKOO, H ^{[1
]}

NISHI, M ^{[1
]}

TANAKA, M ^{[1
]}

机构：

[1] KURUME UNIV, SCH MED, DEPT PHARMACOL, KURUME, FUKUOKA 830, JAPAN

来源：

NEUROSCIENCE LETTERS | 1993年 / 162卷 / 1-2期

关键词：

SEROTONIN; AMYGDALA; PREFRONTAL CORTEX; IN-VIVO MICRODIALYSIS; PSYCHOLOGICAL STRESS; EMOTION;

D O I：

10.1016/0304-3940(93)90565-3

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The effects of psychological stress on serotonin (5-HT) release were studied in the basolateral amygdaloid nucleus and the prefrontal cortex in conscious rats with in vivo microdialysis. Psychological stress, wherein emotional factors were predominantly involved, significantly increased extracellular 5-HT levels in these two areas. These findings suggest that activation of serotonergic neurons in these brain regions is involved in the emotional and/or cognitive states in animals.

引用

页码：81 / 84

页数：4

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