DESIGN AND SYNTHESIS OF A NOVEL SITE-DIRECTED REDUCING AGENT FOR THE DISULFIDE BOND INVOLVED IN THE ACETYLCHOLINE BINDING-SITE OF THE ACHOR

被引：6

作者：

KESSLER, P

SERVENT, D

HIRTH, C

机构：

[1] CEA, Département d'Ingéniérie et d'Etudes des Protéines (DIEP)

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 39期

关键词：

D O I：

10.1016/0040-4039(94)85370-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The 2-trimethylammonioethyloxycarbonylamino-1,4-butanedithiol 7 was synthesized and tested as a site-directed reducing agent for the disulfide bond involved in the acetylcholine binding site of the AChoR, which was then specifically labeled by an undecagold cluster.

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页码：7237 / 7240

页数：4

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