A SHORT-STEP SYNTHESIS OF 14,15-DINOREUDESMANOLIDES USING INTRAMOLECULAR CYCLIZATION OF AN ALLYLSILANE

被引：28

作者：

KURODA, C

SHIMIZU, S

SATOH, JY

机构：

[1] Department of Chemistry, St. Paul's (Rikkyo) University, Toshima-ku

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1990年 / 03期

关键词：

D O I：

10.1039/p19900000519

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

14,15-Dinoreudesman-12,6-olides, α-methylene-γ-lactones fused to a trans-decalin ring with all three possible stereochemistries, were synthesized from a simple dialdehyde monoacetal via intramolecular cyclization of ethyl 5-(2-formylcyclohexyl)-2-(trimethylsilylmethyl)pent-2-enoate. The stereoselectivity of the cyclization reaction is described.

引用

页码：519 / 524

页数：6