3 STATES CRITERION OF NUCLEOPHILIC REACTIVITY IN CONJUGATE ACID OF AN ANIONIC NUCLEOPHILE AND SOME PROBLEMS OF PROTON PARTITIONING - IMPLICATIONS FOR REACTIONS OF 2,2'-DIPYRIDYL DISULFIDE WITH PAPAIN AND WITH L-ERGOTHIONEINE

被引：35

作者：

BROCKLEHURST, K ^{[1
]}

机构：

[1] UNIV LONDON, ST BARTHOLOMEWS HOSP,MED COLL,DEPT BIOCHEM & CHEM, CHARTERHOUSE SQ, LONDON EC1M 6BQ, ENGLAND

来源：

TETRAHEDRON | 1974年 / 30卷 / 15期

关键词：

D O I：

10.1016/S0040-4020(01)97109-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

引用

页码：2397 / 2407

页数：11

共 21 条

[1] INVESTIGATION OF ACTIVE-SITE OF PAPAIN WITH FLUORESCENT PROBES [J].

ALLEN, G ;

LOWE, G .

BIOCHEMICAL JOURNAL, 1973, 133 (04) :679-686

[2]

BENDER ML, 1972, MECHANISMS HOMOGENEO

[3] PROPAPAIN AND ITS CONVERSION TO PAPAIN - NEW TYPE OF ZYMOGEN ACTIVATION MECHANISM INVOLVING INTRAMOLECULAR THIOL-DISULFIDE INTERCHANGE [J].

BROCKLEHURST, K ;

KIERSTAN, MP .

NATURE-NEW BIOLOGY, 1973, 242 (119) :167-170

[4] COVALENT CHROMATOGRAPHY - PREPARATION OF FULLY ACTIVE PAPAIN FROM DRIED PAPAYA-LATEX [J].

BROCKLEHURST, K ;

CARLSSON, J ;

KIERSTAN, MP ;

CROOK, EM .

BIOCHEMICAL JOURNAL, 1973, 133 (03) :573-584

[5] KINETICS AND MECHANISM OF REACTION OF 4(5)-FORMYLIMIDAZOLE WITH HYDROXYLAMINE [J].

BROCKLEHURST, K ;

GRIFFITH.JR .

TETRAHEDRON, 1968, 24 (06) :2407-+

[6] A NOVEL REACTIVITY OF PAPAIN AND A CONVENIENT ACTIVE SITE TITRATION IN PRESENCE OF OTHER THIOLS [J].

BROCKLEHURST, K ;

LITTLE, G .

FEBS LETTERS, 1970, 9 (02) :113-+

[7] REACTIONS OF PAPAIN AND OF LOW-MOLECULAR-WEIGHT THIOLS WITH SOME AROMATIC DISULFIDES - 2,2'-DIPYRIDYL DISULFIDE AS A CONVENIENT ACTIVE-SITE TITRANT FOR PAPAIN EVEN IN PRESENCE OF OTHER THIOLS [J].

BROCKLEHURST, K ;

LITTLE, G .

BIOCHEMICAL JOURNAL, 1973, 133 (01) :67-80

[8] REACTIVITIES OF VARIOUS PROTONIC STATES IN REACTIONS OF PAPAIN AND OF L-CYSTEINE WITH 2,2'-DIPYRIDYL DISULFIDE AND WITH 4,4'-DIPYRIDYL DISULFIDE - EVIDENCE FOR NUCLEOPHILIC REACTIVITY IN UNIONIZED THIOL GROUP OF CYSTEINE-25 RESIDUE OF PAPAIN OCCASSIONED BY ITS INTERACTION WITH HISTIDINE-159-ASPARAGINE-175 HYDROGEN-BONDED SYSTEM [J].

BROCKLEHURST, K ;

LITTLE, G .

BIOCHEMICAL JOURNAL, 1972, 128 (02) :471-+

[9] REACTIONS OF L-ERGOTHIONEINE AND SOME OTHER AMINOTHIONES WITH 2,2'-DIPYRIDYL AND 4,4'-DIPYRIDYL DISULFIDES AND OF L-ERGOTHIONEINE WITH IODOACETAMIDE - 2-MERCAPTOIMIDAZOLES, 2-THIOPYRIDONES AND 4-THIOPYRIDONES, THIOUREA AND THIOACETAMIDE AS HIGHLY REACTIVE NEUTRAL SULFUR NUCLEOPHILES [J].

CARLSSON, J ;

KIERSTAN, MP ;

BROCKLEHURST, K .

BIOCHEMICAL JOURNAL, 1974, 139 (01) :221-235

[10]

CHAIKEN IM, 1969, J BIOL CHEM, V244, P5095

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