AN ELECTROPHORETIC COMPARISON OF HUMAN SERUM ALBUMIN VARIANTS - 8 DISTINGUISHABLE TYPES

被引:48
作者
WEITKAMP, LR
FRANGLEN, G
ROKALA, DA
POLESKY, HF
SIMPSON, NE
SUNDERMAN, FW
BELL, HE
SAAVE, J
LISKER, R
BOHLS, SW
机构
[1] Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI
[2] Chemical Pathology Department, St. George's Hospital Medical School, London
[3] Minneapolis War Memorial Blood Bank, Minneapolis, MN
[4] Department of Pediatrics, Queen's University, Kingston, ON
[5] Department of Laboratory Medicine, University of Connecticut School of Medicine, Hartford, CT
[6] Department of Clinical Laboratories, University of Alberta Hospital, Edmon-ton, AB
[7] Central Malaria Laboratory, Department of Public Health, Konedobu, Port Moresby
[8] Department of Genetics, Instituto Nacional de la Nutrición, Mexico, DF
[9] Austin State Hospital, Austin, TX
关键词
D O I
10.1159/000152212
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Human serum albumin variants from 35 unrelated families have been compared in four electrophorctic systems: a total of eight different classes of variant albumins were identified. The value of using multiple electrophoretic systems to distinguish variants is indicated by the fact that the relative orders of the mobilities of the variants differed among systems and that it was not possible to recognize in any single system more than seven of the eiglit types of variants. In most instances the variants within a class have been found in individuals with an ethnically similar origin. However, the variants from one British family, one Greek family, and a family of New Guinea indigenes were found to be indistinguishable in each of the four electrophoretic systems. © 1969 S. Karger AG, Basel.
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页码:159 / +
页数:1
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