EFFECTS OF PERINATAL DIAZEPAM EXPOSURE ON THE SEXUALLY DIMORPHIC RAT LOCUS-CERULEUS

被引：18

作者：

RODRIGUEZZAFRA, M ^{[1
]}

DEBLAS, MR ^{[1
]}

PEREZLASO, C ^{[1
]}

CALES, JM ^{[1
]}

GUILLAMON, A ^{[1
]}

SEGOVIA, S ^{[1
]}

机构：

[1] UNIV NACL EDUC DISTANCIA, DEPT PSICOBIOL, CIUDAD UNIV, POB 50487, E-28040 MADRID, SPAIN

来源：

NEUROTOXICOLOGY AND TERATOLOGY | 1993年 / 15卷 / 02期

关键词：

SEX DIFFERENCES; DIAZEPAM; NEUROTERATOLOGY; LOCUS-CERULEUS;

D O I：

10.1016/0892-0362(93)90072-V

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Diazepam (DZ) administration over prenatal, postnatal, and pre plus postnatal periods altered the normal expression of the morphological sex differences of the LC. Males were affected only by the prenatal exposure and the effect of this exposure produced an increase in the volume and neuron number of male's LC. By contrast, females were affected by both pre and postnatal treatments and the effect of this exposure resulted in a decrease in the volume and neuron number of female's LC. However, pre plus postnatal treatment did not affect female's LC.

引用

页码：139 / 144

页数：6