SEASONAL-VARIATION IN ETIOLOGY OF TRAVELERS DIARRHEA

被引:66
作者
MATTILA, L
SIITONEN, A
KYRONSEPPA, H
SIMULA, I
OKSANEN, P
STENVIK, M
SALO, P
PELTOLA, H
机构
[1] NATL PUBL HLTH INST,SF-00280 HELSINKI 28,FINLAND
[2] AURORA HOSP,SF-00250 HELSINKI,FINLAND
[3] FINNAIR,HELSINKI,FINLAND
[4] UNIV HELSINKI,CHILDRENS HOSP,SF-00100 HELSINKI 10,FINLAND
[5] JORVI HOSP,ESPOO,FINLAND
关键词
D O I
10.1093/infdis/165.2.385
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The etiology of travelers' diarrhea was studied in 579 adult Finnish tourists participating in two packaged tours to Morocco in the winter (n = 233) and fall (n = 346) of 1989. A research team accompanied the travelers, and a laboratory for enteric pathogens was established in Agadir. At least one pathogen was found in 62% of the 60 diarrhea cases in winter and in 58% of the 111 diarrhea cases in fall. Multiple pathogens were found less often in winter (8%) than in fall (21%, P < .05). Campylobacter strains were the leading cause of travelers' diarrhea in winter, found alone or with other pathogens in 28% of the cases (but in only 7% in fall), whereas enterotoxigenic Escherichia coli (ETEC) was the most common pathogen in fall, present in 32% of the cases (8% in winter). Both differences are highly significant (P < .001). Salmonella enterica was almost as common as ETEC in fall (25% of diarrhea cases) but rare in winter (10%, P < .05). Thus, the etiology of travelers' diarrhea varied according to the season in the same tourist destination. This finding has relevance to both antimicrobial treatment and prophylaxis.
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页码:385 / 388
页数:4
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