THE MOLECULAR AND BIOCHEMICAL BASIS OF DUCHENNE MUSCULAR-DYSTROPHY

被引：64

作者：

ANDERSON, MS ^{[1
]}

KUNKEL, LM ^{[1
]}

机构：

[1] HARVARD UNIV,CHILDRENS HOSP,SCH MED,DIV GENET,BOSTON,MA 02115

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1992年 / 17卷 / 08期

关键词：

D O I：

10.1016/0968-0004(92)90437-E

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Duchenne and Becker muscular dystrophy (DMD, BMD) have both been clinically recognized for over 100 years, yet throughout much of that time nothing beyond clinical evaluation and supportive care during the disease course was available to patients. The identification of the molecular basis of DMD/BMD in 19861,2 paved the way for extensive progress toward the understanding, diagnosis and treatment of this disease.

引用

页码：289 / 292

页数：4