MOTOR-ACTIVITY CORRELATES NEGATIVELY WITH FREE-RUNNING PERIOD, WHILE POSITIVELY WITH SEROTONIN CONTENTS IN SCN IN FREE-RUNNING RATS

被引：67

作者：

SHIOIRI, T ^{[1
]}

TAKAHASHI, K ^{[1
]}

YAMADA, N ^{[1
]}

TAKAHASHI, S ^{[1
]}

机构：

[1] NATL CTR NEUROL & PSYCHIAT,NATL INST NEUROSCI,DIV MENTAL DISORDERS RES,KODAIRA,TOKYO,JAPAN

来源：

PHYSIOLOGY & BEHAVIOR | 1991年 / 49卷 / 04期

关键词：

MOTOR ACTIVITY; RUNNING WHEEL; FREE-RUNNING PERIOD; SEROTONIN; DOPAMINE; NOREPINEPHRINE;

D O I：

10.1016/0031-9384(91)90318-I

中图分类号：

B84 [心理学];

学科分类号：

04 ; 0402 ;

摘要：

Free-running period of blinded rats kept in a cage with a running wheel varied markedly, while it varied little in rats kept in a cage without a running wheel. The mean free-running period of the former group is significantly shorter than that of the latter. In the former, the free-running period correlated negatively with motor activity, indicating that activity affects the free-running period. In both groups, essentially similar diurnal patterns of biogenic amines and their metabolites were observed in various discrete areas in the brain examined. However, there was a significant difference between the two groups in several areas. In the SCN, 5-HT content correlated positively with motor activity, consequently correlated negatively to the free-running period at 3 out of 4 sampling times over 24 h but no such correlation was observed in other monoamines and their metabolites examined. These facts suggest that 5-HT may be associated with modification of the free-running period.

引用

页码：779 / 786

页数：8

共 41 条

[1] EXOGENOUS AND ENDOGENOUS COMPONENTS IN CIRCADIAN RHYTHMS [J].

ASCHOFF, J .

COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, 1960, 25 :11-28

[2] CIRCADIAN-RHYTHMS OF LOCOMOTOR ACTIVITY IN GOLDEN-HAMSTER (MESOCRICETUS-AURATUS) MEASURED WITH 2 DIFFERENT TECHNIQUES [J].

ASCHOFF, J ;

FIGALA, J ;

POPPEL, E .

JOURNAL OF COMPARATIVE AND PHYSIOLOGICAL PSYCHOLOGY, 1973, 85 (01) :20-28

[3] AN EFFECT OF HEAVY WATER ON THE PHASE AND PERIOD OF THE CIRCADIAN RHYTHM IN EUGLENA [J].

BRUCE, VG ;

PITTENDRIGH, CS .

JOURNAL OF CELLULAR AND COMPARATIVE PHYSIOLOGY, 1960, 56 (01) :25-31

[4]

DANN S, 1975, P NATL ACAD SCI USA, V72, P3744

[5]

DANN S, 1976, J COMP PHYSL, V106, P267

[6] HEAVY WATER SLOWS BIOLOGICAL TIMING PROCESSES [J].

ENRIGHT, JT .

ZEITSCHRIFT FUR VERGLEICHENDE PHYSIOLOGIE, 1971, 72 (01) :1-&

[7]

ENRIGHT JT, 1984, MATH MODELS CIRCADIA, P1

[8] PHOTOPERIODIC REGULATION OF HAMSTER TESTIS - DEPENDENCE ON CIRCADIAN-RHYTHMS [J].

ESKES, GA ;

ZUCKER, I .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1978, 75 (02) :1034-1038

[9] MECHANISM FOR SHIFTING THE PHASE OF A CIRCADIAN-RHYTHM BY SEROTONIN - INVOLVEMENT OF CAMP [J].

ESKIN, A ;

CORRENT, G ;

LIN, CY ;

MCADOO, DJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1982, 79 (02) :660-664

[10] VOLTAMMETRIC MEASUREMENTS OF 5-HYDROXYINDOLE COMPOUNDS IN THE SUPRACHIASMATIC NUCLEI - CIRCADIAN FLUCTUATIONS [J].

FARADJI, H ;

CESPUGLIO, R ;

JOUVET, M .

BRAIN RESEARCH, 1983, 279 (1-2) :111-119

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