LACK OF ASSOCIATION BETWEEN BIPOLAR AFFECTIVE-DISORDER AND TYROSINE-HYDROXYLASE DNA MARKER

被引:31
作者
INAYAMA, Y
YONEDA, H
SAKAI, T
ISHIDA, T
KOBAYASHI, S
NONOMURA, Y
KONO, Y
KOH, J
ASABA, H
机构
[1] Department of Neuropsychiatry, Osaka Medical College, Takatsuki, Osaka 569
来源
AMERICAN JOURNAL OF MEDICAL GENETICS | 1993年 / 48卷 / 02期
关键词
ASSOCIATION STUDY; TH LOCUS; CHROMOSOME-11; RFLPS; SOUTHERN BLOTTING;
D O I
10.1002/ajmg.1320480206
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Sixty-eight patients with bipolar affective disorder and 88 controls were investigated for genetic association of tyrosine hydroxylase (TH) restriction fragment length polymorphisms (RFLPs). No significant association between bipolar affective disorder and TH was found. Thus the hypothesis that TH is involved in the pathogenesis of bipolar affective disorder was not supported. (C) 1993 Wiley-Liss, Inc.
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收藏
页码:87 / 89
页数:3
相关论文
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[21]  
YONEDA H, 1992, AM J HUM GENET, V51, P1173