HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 AND HEPATITIS-B VIRUS TRANSCRIPTION IN PERIPHERAL-BLOOD LYMPHOCYTES FROM CO-INFECTED SUBJECTS

被引：9

作者：

CLEMENTI, M ^{[1
]}

MANZIN, A ^{[1
]}

BAGNARELLI, P ^{[1
]}

MENZO, S ^{[1
]}

VARALDO, PE ^{[1
]}

CARLONI, G ^{[1
]}

机构：

[1] CNR,DEPT EXPTL MED,ROME,ITALY

来源：

ARCHIVES OF VIROLOGY | 1992年 / 126卷 / 1-4期

关键词：

D O I：

10.1007/BF01309679

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The molecular characteristics of peripheral blood lymphocyte (PBL) infection by hepatitis B virus (HBV) were studied in human immunodeficiency virus type 1 (HIV-1) infected subjects using highly sensitive polymerase chain reaction (PCR) based techniques. DNA and RNA samples were purified from PBLs of HIV-1 infected individuals, regardless of their HBV serological status and assayed using PCR and reverse-transcription (RT) PCR, respectively. The data shown here are an extension of previous reports documenting HBV and HIV-1 co-infection of PBLs and indicate that transcriptionally active HBV infection of PBLs is detectable in a significant proportion of asymptomatic HIV-1 infected patients.

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页码：1 / 9

页数：9

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