HIGH-PERFORMANCE CAPILLARY ELECTROPHORETIC ANALYSIS OF INFLAMMATORY CYTOKINES IN HUMAN BIOPSIES

被引：28

作者：

PHILLIPS, TM

KIMMEL, PL

机构：

[1] Immunochemistry Laboratory, Division of Renal Diseases and Hypertension, Department of Medicine, Washington, DC 20037, 413 Ross Hall

来源：

JOURNAL OF CHROMATOGRAPHY B-BIOMEDICAL APPLICATIONS | 1994年 / 656卷 / 01期

关键词：

D O I：

10.1016/0378-4347(94)00036-0

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The detection of inflammatory citokines in pathological tissue samples is important as an indicator of disease severity and persistence. Capillary zone electrophoresis (CZE) has been shown to be a good technique for the detection and measurement of tissue-bound citokines in frozen biopsy specimens. CZE separations in polyethylene glycol-coated capillaries, performed at neutral pH and sub-ambient temperatures was found to give the most consistent and reliable results.

引用

页码：259 / 266

页数：8

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