COMMON ANTIGENIC SPECIFICITY ON H-CHAINS OF CHICKEN IGM AND IGG

被引:8
作者
SKAMENE, E
IVANYI, J
机构
[1] Institute of Experimental Biology and Genetics, Czechoslovak Academy of Sciences, Praha
来源
IMMUNOCHEMISTRY | 1969年 / 6卷 / 05期
关键词
D O I
10.1016/0019-2791(67)90137-1
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A common antigenic determinant present on the H-chain of chicken IgG and IgM was revealed by the use of rabbit antisera absorbed with L-chains. Sera of rabbits immunized with γ-chains cross-reacted with IgM. This did not occur if the intact IgG molecule was used for immunization. Sera of rabbits immunized with IgM cross-reacted with γ-chains but not with IgG. These findings indicate a common determinant on the H-chains, 'hidden' in the IgG molecule, but accessible on the IgM molecule. © 1969.
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页码:733 / &
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