A POLYMER-SUPPORTED C-2-SYMMETRICAL CHIRAL AUXILIARY - PREPARATION OF NON-RACEMIC 3,5-DISUBSTITUTED-GAMMA-BUTYROLACTONES

被引：83

作者：

MOON, H ^{[1
]}

SCHORE, NE ^{[1
]}

KURTH, MJ ^{[1
]}

机构：

[1] UNIV CALIF DAVIS,DEPT CHEM,DAVIS,CA 95616

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 48期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/0040-4039(94)88388-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A polymer-bound ''C-2-symmetric'' pyrrolidine-based auxiliary is reported and shown to serve an effective control element for a three-step process consisting of N-acylation, C alpha-alkylation, and subsequent iodolactonization to deliver optically active 3,5-disubstituted-gamma butyrolactone.

引用

页码：8915 / 8918

页数：4

共 41 条

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