MULTICENTER CLINICAL-TRIAL OF IBUPROFEN AND ACETAMINOPHEN IN THE TREATMENT OF POSTOPERATIVE DENTAL PAIN

被引：60

作者：

MEHLISCH, DR

SOLLECITO, WA

HELFRICK, JF

LEIBOLD, DG

MARKOWITZ, R

SCHOW, CE

SHULTZ, R

WAITE, DE

机构：

[1] BIOMED RES GRP,AUSTIN,TX

[2] QUINTILES INC,CHAPEL HILL,NC

[3] UNIV TEXAS,HLTH SCI CTR,DEPT ORAL & MAXILLOFACIAL SURG,HOUSTON,TX 77225

[4] UNIV TEXAS,SCH DENT,DIV ORAL & MAXILLOFACIAL SURG,SAN ANTONIO,TX 78285

[5] UNIV OKLAHOMA,HLTH SCI CTR,COLL MED & DENT,DEPT ORAL & MAXILLOFACIAL SURG,OKLAHOMA CITY,OK 73190

[6] UNIV TEXAS,MED BRANCH,DEPT SURG,DIV ORAL & MAXILLOFACIAL SURG,GALVESTON,TX 77550

[7] UNIV MISSOURI,SCH DENT,DEPT ORAL & MAXILLOFACIAL SURG,KANSAS CITY,MO 64110

[8] BAYLOR COLL DENT,DEPT ORAL & MAXILLOFACIAL SURG,DALLAS,TX 75246

来源：

JOURNAL OF THE AMERICAN DENTAL ASSOCIATION | 1990年 / 121卷 / 02期

关键词：

D O I：

10.14219/jada.archive.1990.0237

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Pharmacological management of pain for acute and chronic conditions has been guided by a scientific understanding of peripheral and central acting mechanisms for the control of inflammation as well as pain. Oral surgery pain is a reliable model to reference the effectiveness of commonly used analgesics such as ibuprofen and acetaminophen. A total of 706 patients who were experiencing moderate to severe pain received a single dose of ibuprofen, acetaminophen, or placebo. After 6 hours, the degree of pain relief and tolerance was assessed. Ibuprofen has important implications for postoperative pain in clinical practice.

引用

页码：257 / 263

页数：7