OXYGEN-TENSION MAPPING WITH F-19 ECHO-PLANAR MR-IMAGING OF SEQUESTERED PERFLUOROCARBON

被引：32

作者：

BARKER, BR ^{[1
]}

MASON, RP ^{[1
]}

BANSAL, N ^{[1
]}

PESHOCK, RM ^{[1
]}

机构：

[1] UNIV TEXAS,SW MED CTR,DEPT RADIOL,E6-228B,5323 HARRY HINES BLVD,DALLAS,TX 75235

来源：

JMRI-JOURNAL OF MAGNETIC RESONANCE IMAGING | 1994年 / 4卷 / 04期

关键词：

FLUORINE STUDIES; LIVER; MR; OXYGEN; PERFLUBRON; RELAXOMETRY;

D O I：

10.1002/jmri.1880040414

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

The authors used fluorine-19 inversion-recovery (IR) echo-planar imaging (EPI) to map oxygen tension on the basis of the spin-lattice relaxation rate (R1) of sequestered perfluorocarbon. R1 measured with IR-EPI varied as a linear function of oxygen tension and temperature, and the relationship agreed well with earlier spectroscopic findings. Oxygen tension maps of a mouse that had received a dose of perflubron emulsion were acquired before, during, and after the mouse breathed pure oxygen. Results showed low liver oxygen tension during air breathing, which increased during breathing of pure oxygen, with distinct regional heterogeneity, to 8-17 %atm (60-130 torr [8.0-17.3 kPa]).

引用

页码：595 / 602

页数：8

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