When a strain of S. cerevisiae monosomic for chromosome I and initially deficient for 25% of the genes coding for rRNA is repeatedly subcultured, the number of these genes increases to and remains stable at the number in the wild type. This strain shows 2:2, viable; inviable 1st division segregation and hemizygosity for the ade1 gene (a chromosome I marker), evidence that the strain is still monosomic for chromosome I. The increase in the number of genes coding for rRNA in yeast may be analogous to the magnification of the rRNA genes in Drosophila melanogaster bobbed mutants.
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页码:1177 / 1180
页数:4
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