MAGNIFICATION OF GENES CODING FOR RIBOSOMAL-RNA IN SACCHAROMYCES-CEREVISIAE

被引:23
作者
KABACK, DB
HALVORSON, HO
机构
[1] BRANDEIS UNIV, DEPT BIOL, WALTHAM, MA 02154 USA
[2] BRANDEIS UNIV, ROSENSTIEL BAS MED SCI RES CTR, WALTHAM, MA 02154 USA
关键词
D O I
10.1073/pnas.74.3.1177
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
When a strain of S. cerevisiae monosomic for chromosome I and initially deficient for 25% of the genes coding for rRNA is repeatedly subcultured, the number of these genes increases to and remains stable at the number in the wild type. This strain shows 2:2, viable; inviable 1st division segregation and hemizygosity for the ade1 gene (a chromosome I marker), evidence that the strain is still monosomic for chromosome I. The increase in the number of genes coding for rRNA in yeast may be analogous to the magnification of the rRNA genes in Drosophila melanogaster bobbed mutants.
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页码:1177 / 1180
页数:4
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