IRREVERSIBLE ENZYME INHIBITORS .179. ACTIVE-SITE-DIRECTEC IRREVERSIBLE ENZYME INHIBITORS OF DIHYDROFOLATE REDUCTASE FROM 1-(3-CHLOROPHENYL)-4,6-DIAMINO-1,2-DIHYDRO-2,2-DIMETHYL-S-TRIAZINE WITH OXYAMIDE BRIDGES TO A TERMINAL SULFONYL FLUORIDE

被引：9

作者：

BAKER, BR

ASHTON, WT

机构：

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1970年 / 13卷 / 06期

关键词：

D O I：

10.1021/jm00300a032

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

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页码：1165 / &

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[1] IRREVERSIBLE ENZYME INHIBITORS .160. SOME FACTORS IN CELL WALL TRANSPORT OF ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITORS OF DIHYDROFOLIC REDUCTASE DERIVED FROM 4,6-DIAMINO-1,2-DIHYDRO-2,2-DIMETHYL-L-(PHENYLALKYLPHENYL)-S-TRIAZINES
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[2] IRREVERSIBLE ENZYME INHIBITORS .159. EFFECT OF SUBSTITUTION ON TRANSPORT AND ISOZYME SPECIFICITY OF P-(4,6-DIAMINO-1,2-DIHYDRO-2,2-DIMETHYL-S-TRIAZIN-L-YL)-O-CHLOROPHENOXYACETAMIDO-BENZENESULFONYL FLUORIDE, AN ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITOR OF DIHYDROFOLIC REDUCTASE
BAKER, BR
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[3] IRREVERSIBLE ENZYME INHIBITORS .175. IRREVERSIBLE INHIBITION OF PURIFIED DIHYDROFOLIC REDUCTASE
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[4] IRREVERSIBLE ENZYME INHIBITORS .154. SOME FACTORS IN CELL WALL TRANSPORT OF ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITORS OF DIHYDROFOLIC REDUCTASE DERIVED FROM 5-SUBSTITUTED 2,4-DIAMINOPYRIMIDINES
BAKER, BR
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[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1969, 12 (04) : 668 - &
[5] IRREVERSIBLE ENZYME INHIBITORS . 140 . ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITORS DERIVED FROM 1-(3-CHLOROPHENYL)-4,6-DIAMINO-1,2-DIHYDRO-2,2-DIMETHYL-S-TRIAZINE
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[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1969, 12 (01) : 95 - &
[6] IRREVERSIBLE ENZYME INHIBITORS . 133 . STUDIES ON DIFFERENTIAL IRREVERSIBLE INHIBITION OF DIHYDROFOLIC REDUCTASE FROM 3 STRAINS OF L1210 LEUKEMIA LIVER SPLEEN AND INTESTINE OF MOUSE
BAKER, BR
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[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1969, 12 (01) : 67 - +
[7] IRREVERSIBLE ENZYME INHIBITORS .173. CURE OF WALKER-256 ASCITES BY RVERSIBLE AND IRREVERSIBLE INHIBITORS OF DIHYDROFOLIC REDUCTASE DERIVED FROM 1-(SUBSTITUTED-PHENYL)-4,6-DIAMINO-1,2-DIHYDRO-2,2-DIMETHYL-S-TRIAZINE
BAKER, BR
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[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1970, 13 (06) : 1130 - +
[8] IRREVERSIBLE ENZYME INHIBITORS .177. ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITORS OF DIHYDROFOLATE REDUCTASE DERIVED FROM 4,6-DIAMINO-1, - DIHYDRO-2,2-DIMETHYL-1-(PHENYLALKYLPHENYL)-S-TRIAZINES .2.
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