EFFECTS OF LIPOPOLYSACCHARIDES AND PROSTAGLANDINS ON RAT BONE CELL CALCIUM AND CYCLIC-AMP

被引:16
作者
DZIAK, R
HAUSMANN, E
CHANG, YW
机构
[1] Department of Oral Biology, School of Dentistry, State University of New York at Buffalo, Buffalo
关键词
D O I
10.1016/0003-9969(79)90101-8
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Bone cells were isolated by collagenase digestion of 19-21 day old fetal rat calvaria. At 37 °C, lipopolysaccharides decreased Ca uptake 30-70 per cent below control values. At 4 °C, 100-900 per cent increases in Ca uptake were observed. Incubation with lipid A produced similar effects. No effects of lipopolysaccharides on cyclic AMP were noted. Prostaglandins E1, E2 and A1 had no effects on calcium transport but produced characteristic increases in cyclic AMP. © 1979.
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页码:347 / 353
页数:7
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