CYTOGENETIC CHANGES IN WHITE BLOOD CELLS AFTER CYCLOPHOSPHAMIDE TREATMENT

被引：26

作者：

BAUCHINGER, M

SCHMID, E

机构：

[1] Institut für Biologie der Gesellschaft für Strahlenforschung, München-Neuherberg und Strahlenbiologisches Institut der Universität München, München

来源：

ZEITSCHRIFT FUR KREBSFORSCHUNG | 1969年 / 72卷 / 01期

关键词：

D O I：

10.1007/BF00524798

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The chromosome analysis of 19 non-irradiated patients with ovarian tumours showed a mean of 15-20% chromosomal defects of all analysed cells. The corresponding value of non-irradiated tumour patients without cytostatic treatment was 2.5%. The number of breaks per analysed cell was about 10 times greater than in these controlls. Most of the defects are formed by aberrations of chromatids of the delayed-isolocus" type. The abnormalities increase with the number of single infusions and the dose of cyclophosphamide. © 1969 Springer-Verlag."

引用

页码：77 / +

页数：1

共 21 条

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VALERIOTE, FA
COLLINS, DC
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[J]. RADIATION RESEARCH, 1968, 33 (03) : 501 - +

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