POLYOMA-VIRUS - EARLY REGION AND ITS T-ANTIGENS

被引：28

作者：

SOEDA, E ^{[1
]}

ARRAND, JR ^{[1
]}

GRIFFIN, BE ^{[1
]}

机构：

[1] IMPERIAL CANC RES FUND,LONDON WC2A 3PX,ENGLAND

来源：

NUCLEIC ACIDS RESEARCH | 1979年 / 7卷 / 04期

关键词：

D O I：

10.1093/nar/7.4.839

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The DNA sequence of the early coding region of polyoma virus is presented. It consists of 2739 nucleotides. The sequence predicts that more than one reading frame can be used to code for the three known polyoma virus early proteins (designated small, middle and large T-antigens). From the DNA sequence, the 'splicing' signals used in the processing of viral RNA to functional messenger RNAs can be predicted, as well as the sizes and sequences of the three proteins. Other unusual aspects of the DNA sequence are noted. Comparisons are made between the DNA sequences and the predicted amino acid sequences of the respective large T-antigens of polyoma virus and the related virus Simian Virus (SV) 40. © 1979 Information Retrieval Limited.

引用

收藏

页码：839 / 857

页数：19

相关论文

共 35 条

[1] OVALBUMIN GENE - EVIDENCE FOR A LEADER SEQUENCE IN MESSENGER-RNA AND DNA SEQUENCES AT EXON-INTRON BOUNDARIES [J].

BREATHNACH, R ;

BENOIST, C ;

OHARE, K ;

GANNON, F ;

CHAMBON, P .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1978, 75 (10) :4853-4857

[2]

EISSENBERG S, 1977, P NATL ACAD SCI US, V74, P3198

[3] LOCALIZATION OF GENE FUNCTIONS IN POLYOMA-VIRUS DNA [J].

FEUNTEUN, J ;

SOMPAYRAC, L ;

FLUCK, M ;

BENJAMIN, T .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1976, 73 (11) :4169-4173

[4] COMPLETE NUCLEOTIDE-SEQUENCE OF SV40 DNA [J].

FIERS, W ;

CONTRERAS, R ;

HAEGEMAN, G ;

ROGIERS, R ;

VANDEVOORDE, A ;

VANHEUVERSWYN, H ;

VANHERREWEGHE, J ;

VOLCKAERT, G ;

YSEBAERT, M .

NATURE, 1978, 273 (5658) :113-120

[5] NUCLEOTIDE-SEQUENCE AND GENOME ORGANIZATION OF THE POLYOMA EARLY REGION - EXTENSIVE NUCLEOTIDE AND AMINO-ACID HOMOLOGY WITH SV40 [J].

FRIEDMANN, T ;

ESTY, A ;

LAPORTE, P ;

DEININGER, P .

CELL, 1979, 17 (03) :715-724

[6] ORGANIZATION AND SEQUENCES AT THE 5' END OF A CLONED COMPLETE OVALBUMIN GENE [J].

GANNON, F ;

OHARE, K ;

PERRIN, F ;

LEPENNEC, JP ;

BENOIST, C ;

COCHET, M ;

BREATHNACH, R ;

ROYAL, A ;

GARAPIN, A ;

CAMI, B ;

CHAMBON, P .

NATURE, 1979, 278 (5703) :428-434

[7] HETEROGENEITY AND 5'-TERMINAL STRUCTURES OF THE LATE RNAS OF SIMIAN-VIRUS-40 [J].

GHOSH, PK ;

REDDY, VB ;

SWINSCOE, J ;

LEBOWITZ, P ;

WEISSMAN, SM .

JOURNAL OF MOLECULAR BIOLOGY, 1978, 126 (04) :813-846

[8] POLYOMA DNA - PHYSICAL MAP [J].

GRIFFIN, BE ;

FRIED, M ;

COWIE, A .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1974, 71 (05) :2077-2081

[9]

GRIFFIN BE, J VIROL

[10] DNA-SEQUENCE ALTERATIONS IN HR-T DELETION MUTANTS OF POLYOMA-VIRUS [J].

HATTORI, J ;

CARMICHAEL, GG ;

BENJAMIN, TL .

CELL, 1979, 16 (03) :505-513

← 1 2 3 4 →