STEREOSELECTIVE SYNTHESIS OF ALCOHOLS .38. STEREOSELECTIVE TOTAL SYNTHESIS OF THE DENTICULATINS

被引：42

作者：

ANDERSEN, MW ^{[1
]}

HILDEBRANDT, B ^{[1
]}

DAHMANN, G ^{[1
]}

HOFFMANN, RW ^{[1
]}

机构：

[1] UNIV MARBURG,FACHBEREICH CHEM,HANS MEERWEIN STR,W-3550 MARBURG,GERMANY

来源：

CHEMISCHE BERICHTE | 1991年 / 124卷 / 09期

关键词：

MARINE NATURAL PRODUCTS; HEMIKETAL FORMATION; SELECTIVE; DENTICULATINS;

D O I：

10.1002/cber.19911240940

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The total synthesis of the denticulatins 1 is described. Key feature is the efficient generation of the C-1-to-C-9 building block 37 by three consecutive stereoselective carbon - carbon bond-forming steps using chiral allylboronates. The C-10-to-C-17 building block was obtained by kinetic Sharpless resolution of an allylic alcohol followed by an Ireland-Claisen rearrangement.

引用

页码：2127 / 2139

页数：13

共 35 条

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