IS THERE A ROLE FOR POSITIVE INOTROPIC AGENTS IN CONGESTIVE-HEART-FAILURE - FOCUS ON MORTALITY

被引:7
作者
AMIDON, TM [1 ]
PARMLEY, WW [1 ]
机构
[1] UNIV CALIF SAN FRANCISCO, DEPT MED, SAN FRANCISCO, CA 94143 USA
关键词
CONGESTIVE HEART FAILURE; INOTROPIC THERAPY; SURVIVAL STUDIES;
D O I
10.1002/clc.4960171203
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Congestive heart failure (CHF) is a common clinical syndrome that may result from a variety of etiologies. Impaired contractility can lead to pump failure and a number of hemodynamic and neurohormonal alterations. Vasodilator therapy improves symptoms and survival in patients with CHF due to systolic dysfunction. Inotropic therapy, on the other hand, has not been shown to improve survival and may even worsen survival. This article reviews the mechanism of action and clinical trials of inotropic therapy in patients with CHF.
引用
收藏
页码:641 / 647
页数:7
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