THE TROPHIC ACTION OF HUMAN GROWTH-HORMONE ON HUMAN DUODENAL MUCOSA CULTURED IN-VITRO

被引:25
作者
CHALLACOMBE, DN
WHEELER, EE
机构
[1] Somerset Children’s Research Unit, Musgrove Park Hospital, Taunton, Somerset
关键词
GROWTH HORMONE; DUODENAL MUCOSA; TROPHIC ACTION;
D O I
10.1097/00005176-199507000-00008
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The influence of human growth hormone (hGH) on crypt cell proliferation in cultured explants of human duodenal mucosa has been studied, using a stathmokinetic technique with crypt microdissection. The addition of hGH (0.004 IU/ml) to paired duodenal explants from eight patients significantly increased epithelial crypt cell proliferation (p < 0.001), showing that hGH has a trophic action on the human duodenal mucosa in vitro.
引用
收藏
页码:50 / 53
页数:4
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