THE TROPHIC ACTION OF HUMAN GROWTH-HORMONE ON HUMAN DUODENAL MUCOSA CULTURED IN-VITRO

被引：25

作者：

CHALLACOMBE, DN

WHEELER, EE

机构：

[1] Somerset Children’s Research Unit, Musgrove Park Hospital, Taunton, Somerset

来源：

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION | 1995年 / 21卷 / 01期

关键词：

GROWTH HORMONE; DUODENAL MUCOSA; TROPHIC ACTION;

D O I：

10.1097/00005176-199507000-00008

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The influence of human growth hormone (hGH) on crypt cell proliferation in cultured explants of human duodenal mucosa has been studied, using a stathmokinetic technique with crypt microdissection. The addition of hGH (0.004 IU/ml) to paired duodenal explants from eight patients significantly increased epithelial crypt cell proliferation (p < 0.001), showing that hGH has a trophic action on the human duodenal mucosa in vitro.

引用

页码：50 / 53

页数：4

共 19 条

[1]

Al-Mukhtar M.Y.T., 1982, MECHANISMS INTESTINA, P3

[2] HUMAN GROWTH-HORMONE INCREASES INTESTINAL VITAMIN-D-DEPENDENT CALCIUM-BINDING PROTEIN IN HYPOPHYSECTOMIZED RATS [J].