PREPARATION AND STUDY OF DINUCLEAR ZINC(II) COMPLEX FOR THE EFFICIENT HYDROLYSIS OF THE PHOSPHODIESTER LINKAGE IN A DIRIBONUCLEOTIDE

被引：129

作者：

YASHIRO, M

ISHIKUBO, A

KOMIYAMA, M

机构：

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1995年 / 17期

关键词：

D O I：

10.1039/c39950001793

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A dinuclear zinc(ll) complex with N,N,N',N'-tetrakis[(2-pyridyl)methyl]-2-hyroxy-1,3-diaminopropane efficiently hydrolyses ApA [adenylyl(3'-5')adenosine] at pH 7 and 50 degrees C; the complex can thus be regarded as a good artificial ribonuclease which effectively mimics enzyme active sites.

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页码：1793 / 1794

页数：2

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