SYNTHESIS AND X-RAY CRYSTAL-STRUCTURE OF A NEW CHOLAPHANE WITH EXTERNALLY DIRECTED FUNCTIONALITY

被引:28
作者
DAVIS, AP [1 ]
ORCHARD, MG [1 ]
SLAWIN, AMZ [1 ]
WILLIAMS, DJ [1 ]
机构
[1] UNIV LONDON IMPERIAL COLL SCI & TECHNOL,DEPT CHEM,LONDON SW7 2AY,ENGLAND
关键词
D O I
10.1039/c39910000612
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The 'cholaphane' 1 was synthesized in 26% overall yield from cholic acid and its structure determined by X-ray crystallography; the molecule adopts an open conformation and is able to surround two molecules of tetrahydrofuran.
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页码:612 / 614
页数:3
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