IMMUNOPATHOGENESIS OF CHRONIC INFLAMMATORY BOWEL-DISEASE

被引:5
作者
BRAEGGER, CP
机构
[1] Department of Paediatrics, University of Zürich
关键词
CROHNS DISEASE; MACROPHAGES; T LYMPHOCYTES; TUMOR NECROSIS FACTOR; ULCERATIVE COLITIS;
D O I
10.1111/j.1651-2227.1994.tb13223.x
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
The aetiology and pathogenesis of chronic inflammatory bowel disease are unknown. However, there is circumstantial evidence that immune mechanisms may play a significant role in mediating the gut lesion and various systemic manifestations. The role of the cellular immune system, soluble mediators, including proinflammatory and immunoregulatory cytokines, humoral immunity and mucosal complement activation will be discussed.
引用
收藏
页码:18 / 21
页数:4
相关论文
共 31 条
  • [31] CIRCULATING ANTIBODIES AGAINST HUMAN COLONIC EXTRACT ENRICHED WITH A 40 KDA PROTEIN IN PATIENTS WITH ULCERATIVE-COLITIS
    TAKAHASI, F
    SHAH, HS
    WISE, LS
    DAS, KM
    [J]. GUT, 1990, 31 (09) : 1016 - 1020