SELECTIVE DIFFERENTIATION OF CD4+ T-HELPER CELL SUBSETS

被引:109
作者
SCOTT, P
机构
[1] School of Veterinary Medicine, University of Pennsylvania, Philadelphia
关键词
D O I
10.1016/0952-7915(93)90058-Z
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
During the past year significant advances have been made in our understanding of the factors contributing to the differentiation of CD4+ T helper cell subsets. These have been driven, in part, by the realization that signals (cytokines) from the innate immune response are critical in T cell subset differentiation. In addition, several studies have also elucidated how the antigen-presenting cell, the antigenic epitope and the antigen concentration may contribute to the selective development of a particular T helper cell subset.
引用
收藏
页码:391 / 397
页数:7
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