ALIPHATIC TRIENE FORMATION DURING THE LUPINUS-ALBUS LIPOXYGENASE-CATALYZED REACTION - COMPARISON WITH DOUBLE DIOXYGENATION OF ARACHIDONIC-ACID BY SOYBEAN LIPOXYGENASE-1

被引：4

作者：

ANDRIANARISON, RH ^{[1
]}

TIXIER, M ^{[1
]}

BENEYTOUT, JL ^{[1
]}

机构：

[1] FAC PHARM LIMOGES, BIOCHIM LAB, 2 RUE DOCTEUR MARCLAND, F-87025 LIMOGES, FRANCE

来源：

PLANT SCIENCE | 1991年 / 75卷 / 02期

关键词：

LIPOXYGENASE; ARACHIDONIC ACID; (LUPINUS-ALBUS);

D O I：

10.1016/0168-9452(91)90236-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Lupinus albus lipoxygenase has been shown to catalyse the formation of a trienoic fatty acid from arachidonic acid. In several ways, the conversion of arachidonic acid to conjugated aliphatic triene by Lupinus albus lipoxygenase bears resemblance with the reaction catalyzed by soybean lipoxygenase-1 in the double dioxygenation of arachidonic acid. Points of similarity include enzymatic removal of a hydrogen at carbon 10, double bond isomerization, and formation of a new carbon-to-oxygen bond. Based on the chromatographic and spectrometric analysis, the double dioxygenated product was identified as 8,15-dihydroperoxy-5,9,11,13-eicosatetraenoic acid.

引用

页码：215 / 220

页数：6

共 17 条

[11] LEUKOTRIENES - MEDIATORS OF IMMEDIATE HYPERSENSITIVITY REACTIONS AND INFLAMMATION [J].

SAMUELSSON, B .

SCIENCE, 1983, 220 (4597) :568-575

[12]

SHIMIZU T, 1987, ADV PROSTAGL THROMB, V717, P64

[13] DOUBLE DIOXYGENATION OF ARACHIDONIC-ACID BY SOYBEAN LIPOXYGENASE-1 - KINETICS AND REGIO-STEREO SPECIFICITIES OF THE REACTION STEPS [J].

VANOS, CPA ;

RIJKESCHILDER, GPM ;

VANHALBEEK, H ;

VERHAGEN, J ;

VLIEGENTHART, JFG .

BIOCHIMICA ET BIOPHYSICA ACTA, 1981, 663 (01) :177-193

[14] THE BIOSYNTHESIS OF JASMONIC ACID - A PHYSIOLOGICAL-ROLE FOR PLANT LIPOXYGENASE [J].

VICK, BA ;

ZIMMERMAN, DC .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1983, 111 (02) :470-477

[15]

YAMAMOTO S, 1988, ANN NY ACAD SCI, V524, P12

[16] CHARACTERIZATION OF A PROSTAGLANDIN-LIKE METABOLITE OF LINOLENIC ACID PRODUCED BY A FLAX-SEED EXTRACT [J].

ZIMMERMAN, DC ;

FENG, P .

LIPIDS, 1978, 13 (05) :313-316

[17] IDENTIFICATION OF TRAUMATIN, A WOUND HORMONE, AS 12-OXO-TRANS-10-DODECENOIC ACID [J].

ZIMMERMAN, DC ;

COUDRON, CA .

PLANT PHYSIOLOGY, 1979, 63 (03) :536-541

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