TOXICITY STUDY OF 1ST AND 2ND GENERATION HYDROGEL-COATED LATEX URINARY CATHETERS

被引：17

作者：

NACEY, JN ^{[1
]}

DELAHUNT, B ^{[1
]}

机构：

[1] WELLINGTON SCH MED,DEPT PATHOL,WELLINGTON,NEW ZEALAND

来源：

BRITISH JOURNAL OF UROLOGY | 1991年 / 67卷 / 03期

关键词：

D O I：

10.1111/j.1464-410X.1991.tb15143.x

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

The hydrogel-coated urinary catheter is a novel formulation in which the coating hydrogel polymer is claimed to reduce the level of cytotoxicity frequently associated with the use of latex catheters. This study was undertaken to measure cytotoxicity using in vivo techniques. Twelve first generation and 5 second generation hydrogel-coated latex catheters were evaluated in vivo using canine urethras. The results showed all catheters to cause minimal inflammatory changes of the urethral mucosa (toxicity score 0-1.2/6).

引用

页码：314 / 316

页数：3

共 14 条

[1]

BROWNE GB, 1893, LANCET, V1, P527

[2] EFFECT OF A HYDROGEL COATING ON THE SURFACE-TOPOGRAPHY OF LATEX-BASED URINARY CATHETERS - AN SEM STUDY [J].