THE GAMMA-FIBRINOGEN GENE (FGG) MAPS TO CHROMOSOME-17 IN BOTH CATTLE AND SHEEP

被引：14

作者：

JOHNSON, SE ^{[1
]}

BARENDSE, W ^{[1
]}

HETZEL, DJS ^{[1
]}

机构：

[1] UNIV QUEENSLAND,CSIRO,DIV TROP ANIM PROD,LEVEL 3,GEHRMANN LABS,RES RD,ST LUCIA,QLD 4072,AUSTRALIA

来源：

CYTOGENETICS AND CELL GENETICS | 1993年 / 62卷 / 2-3期

关键词：

D O I：

10.1159/000133466

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The gamma fibrinogen gene (FGG) was localised in both cattle and sheep using in situ hybridisation. The probe employed was a 1-kb bovine cDNA fragment. Based on observations of QFQ-banded chromosome preparations, this locus is on bovine chromosome 17q12 --> q13 and on the homologous sheep chromosome 17. This localisation is, to our knowledge, the first assignment to chromosome 17 in either the bovine or ovine genome. In addition to localising FGG to this chromosome, the assignment provisionally maps the previously unassigned syntenic group U23, containing (besides FGG) the genes for mitochondrial aldehyde dehydrogenase 2 (ALDH2), interleukin 2 (IL2), immunoglobulin lambda (IGL), and beta fibrinogen (FGB), to chromosome 17 in cattle and probably to the same chromosome in sheep.

引用

页码：176 / 180

页数：5

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