INTESTINAL, SEGMENTED, FILAMENTOUS BACTERIA

被引:34
作者
KLAASEN, HLBM
KOOPMAN, JP
POELMA, FGJ
BEYNEN, AC
机构
[1] CATHOLIC UNIV NIJMEGEN, CENT ANIM LAB, NIJMEGEN, NETHERLANDS
[2] AGR UNIV WAGENINGEN, DEPT HUMAN NUTR, 6700 HB WAGENINGEN, NETHERLANDS
[3] UNIV UTRECHT, DEPT LAB ANIM SCI, UTRECHT, NETHERLANDS
关键词
GASTROINTESTINAL MICROBIOTA; COLONIZATION RESISTANCE; MUCOSA-ASSOCIATED BACTERIA; MOUSE ILEUM; MUCOSAL IMMUNITY;
D O I
10.1016/0378-1097(92)90801-T
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Segmented, filamentous bacteria (SFBs) are autochthonous, apathogenic bacteria, occurring in the ileum of mice and rats. Although the application of formal taxonomic criteria is impossible due to the lack of an in vitro technique to culture SFBs, microbes with a similar morphology, found in the intestine of a wide range of vertebrate and invertebrate host species, are considered to be related. SFBs are firmly attached to the epithelial cells of the distal ileal mucosa, their preferential ecological niche being the epithelium covering the Peyer's patches. Electron microscopic studies have demonstrated a considerable morphological diversity of SFBs, which may relate to different stages of a life cycle. Determinants of SFB colonization in vivo are host species, genotypical and phenotypical characteristics of the host, diet composition, environmental stress and antimicrobial drugs. SFBs can survive in vitro incubation, but do not multiply. On the basis of their apathogenic character and intimate relationship with the host, it is suggested that SFBs contribute to development and/or maintenance of host resistance to enteropathogens.
引用
收藏
页码:165 / 179
页数:15
相关论文
共 105 条
[31]   GNOTOBIOTIC ANIMAL AS A TOOL IN STUDY OF HOST MICROBIAL RELATIONSHIPS [J].
GORDON, HA ;
PESTI, L .
BACTERIOLOGICAL REVIEWS, 1971, 35 (04) :390-+
[32]  
Grasse P., 1925, ANN PARASITOLOGIE HU, V3, P343
[33]   SCANNING ELECTRON-MICROSCOPY OF FILAMENTOUS ORGANISMS ASSOCIATED WITH COCCIDIAL INFECTIONS IN CATS AND SHEEP [J].
GREGORY, MW ;
PITTILO, RM ;
BALL, SJ ;
HUTCHISON, WM .
ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY, 1985, 79 (04) :473-475
[34]  
HAMPTON JC, 1965, LAB INVEST, V14, P1464
[35]   EFFECTS OF NITROGEN MUSTARD ON INTESTINAL EPITHELIUM OF MOUSE [J].
HAMPTON, JC .
RADIATION RESEARCH, 1967, 30 (03) :576-&
[36]  
HAMPTON JC, 1962, 5TH P INT C EL MICR, pLL9
[37]   INTESTINAL COLONIZATION AND VIRULENCE OF SALMONELLA IN MICE [J].
HOHMANN, AW ;
SCHMIDT, G ;
ROWLEY, D .
INFECTION AND IMMUNITY, 1978, 22 (03) :763-770
[38]  
HOSKINS JD, 1982, AM J VET RES, V43, P1715
[39]  
KAUFER I, 1982, FORTSCHRITTE VETERIN, V35, P195
[40]  
KLAASEN H L B, 1991, Microbial Ecology in Health and Disease, V4, P391