SYNTHESIS AND CALCIUM-CHANNEL ANTAGONIST ACTIVITY OF DIALKYL 4-(DIHYDROPYRIDINYL)-1,4-DIHYDRO-2,6-DIMETHYL-3,5-PYRIDINEDICARBOXYLATES

被引：48

作者：

DAGNINO, L

LIKWONGKEN, MC

WYNN, H

WOLOWYK, MW

TRIGGLE, CR

KNAUS, EE

机构：

[1] UNIV ALBERTA,FAC PHARM & PHARMACEUT SCI,EDMONTON T6G 2N8,ALBERTA,CANADA

[2] MEM UNIV NEWFOUNDLAND,FAC MED,ST JOHNS A1B 3V6,NEWFOUNDLAND,CANADA

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1987年 / 30卷 / 04期

关键词：

D O I：

10.1021/jm00387a010

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

收藏

页码：640 / 646

页数：7

相关论文

共 24 条

[1] EFFECTS OF 5 DIFFERENT ORGANIC CALCIUM-ANTAGONISTS ON GUINEA-PIG ISOLATED TRACHEA
ADVENIER, C
CERRINA, J
DUROUX, P
FLOCH, A
RENIER, A
[J]. BRITISH JOURNAL OF PHARMACOLOGY, 1984, 82 (03) : 727 - 733
[2] ANTMAN E, 1983, CALCIUM CHANNEL BLOC, P177
[3] BOLGER GT, 1983, J PHARMACOL EXP THER, V225, P291
[4] QUANTITATIVE ASPECTS OF DRUG-RECEPTOR INTERACTIONS .1. CA2+ AND CHOLINERGIC RECEPTOR ACTIVATION IN SMOOTH-MUSCLE - BASIC MODEL FOR DRUG-RECEPTOR INTERACTIONS
CHANG, KJ
TRIGGLE, DJ
[J]. JOURNAL OF THEORETICAL BIOLOGY, 1973, 40 (01) : 125 - 154
[5] SYNTHESIS AND CALCIUM-CHANNEL ANTAGONIST ACTIVITY OF DIALKYL 1,4-DIHYDRO-2,6-DIMETHYL-4-(PYRIDINYL)-3,5-PYRIDINEDICARBOXYLATES
DAGNINO, L
LIKWONGKEN, MC
WOLOWYK, MW
WYNN, H
TRIGGLE, CR
KNAUS, EE
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1986, 29 (12) : 2524 - 2529
[6] CYCLOADDUCTS OF PHENYLSULFONYL CYANIDE N-OXIDE AND N-SUBSTITUTED 1,2-DIHYDROPYRIDINES - REGIOSPECIFICITY AND STEREOSPECIFICITY
DUBEY, SK
KNAUS, EE
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1984, 49 (01) : 123 - 125
[7] EVIDENCE FOR MULTIPLE RECEPTOR-SITES WITHIN THE PUTATIVE CALCIUM-CHANNEL
FERRY, DR
GLOSSMANN, H
[J]. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 1982, 321 (01) : 80 - 83
[8] CRYSTAL-STRUCTURES AND PHARMACOLOGICAL ACTIVITY OF CALCIUM-CHANNEL ANTAGONISTS - 2,6-DIMETHYL-3,5-DICARBOMETHOXY-4-(UNSUBSTITUTED, 3-METHYL-PHENYL, 4-METHYL-PHENYL, 3-NITRO-PHENYL, 4-NITRO-PHENYL, AND 2,4-DINITROPHENYL)-1,4-DIHYDROPYRIDINE
FOSSHEIM, R
SVARTENG, K
MOSTAD, A
ROMMING, C
SHEFTER, E
TRIGGLE, DJ
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1982, 25 (02) : 126 - 131
[9] FOWLER FW, 1972, J ORG CHEM, V37, P1321
[10] GODFRAIND T, 1982, CALCIUM MODULATORS