ACCESSORY CELL-FUNCTION IN ASYMPTOMATIC HUMAN IMMUNODEFICIENCY VIRUS-INFECTED PATIENTS

被引：29

作者：

CLERICI, M ^{[1
]}

STOCKS, NI ^{[1
]}

ZAJAC, RA ^{[1
]}

BOSWELL, RN ^{[1
]}

SHEARER, GM ^{[1
]}

机构：

[1] SGHMMI,HIV UNIT,LACKLAND AFB,TX 78236

来源：

CLINICAL IMMUNOLOGY AND IMMUNOPATHOLOGY | 1990年 / 54卷 / 02期

关键词：

D O I：

10.1016/0090-1229(90)90078-5

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Peripheral blood mononuclear cells from human immunodeficiency virus seropositive (HIV+) individuals who did not exhibit symptoms of acquired immunodeficiency syndrome (AIDS) (Walter Reed Stage 1 patients) were tested for accessory cell function for presentation of recall antigens to autologous T lymphocytes and for presentation of HLA alloantigens to T lymphocytes from healthy, HIV- donors. Neither experimental model indicated a defect in accessory cell function at this early stage after HIV infection, although our study does not exclude the possibility of accessory cell dysfunction at a later stage of AIDS development. © 1990.

引用

页码：168 / 173

页数：6

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