Microbial Enzymes: Tools for Biotechnological Processes

被引：393

作者：

Adrio, Jose L. ^{[1
]}

Demain, Arnold L. ^{[2
]}

机构：

[1] BIC Granada, Neol Biosolut SA, E-18016 Granada, Spain

[2] Drew Univ, RISE, Madison, NJ 07940 USA

来源：

BIOMOLECULES | 2014年 / 4卷 / 01期

关键词：

biocatalysis; industrial enzymes; microbial hosts; protein engineering;

D O I：

10.3390/biom4010117

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Microbial enzymes are of great importance in the development of industrial bioprocesses. Current applications are focused on many different markets including pulp and paper, leather, detergents and textiles, pharmaceuticals, chemical, food and beverages, biofuels, animal feed and personal care, among others. Today there is a need for new, improved or/and more versatile enzymes in order to develop more novel, sustainable and economically competitive production processes. Microbial diversity and modern molecular techniques, such as metagenomics and genomics, are being used to discover new microbial enzymes whose catalytic properties can be improved/modified by different strategies based on rational, semi-rational and random directed evolution. Most industrial enzymes are recombinant forms produced in bacteria and fungi.

引用

页码：117 / 139

页数：23

共 161 条

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