TOTAL SYNTHESIS OF RAPAMYCIN VIA A NOVEL TITANIUM-MEDIATED ALDOL MACROCYCLIZATION REACTION

被引：103

作者：

HAYWARD, CM ^{[1
]}

YOHANNES, D ^{[1
]}

DANISHEFSKY, SJ ^{[1
]}

机构：

[1] YALE UNIV,DEPT CHEM,NEW HAVEN,CT 06511

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1993年 / 115卷 / 20期

关键词：

D O I：

10.1021/ja00073a083

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

[No abstract available]

引用

页码：9345 / 9346

页数：2

共 47 条

[1] A NOVEL APPLICATION OF THE DESS-MARTIN REAGENT TO THE SYNTHESIS OF AN FK506 ANALOG AND OTHER TRICARBONYL COMPOUNDS
BATCHELOR, MJ
GILLESPIE, RJ
GOLEC, JMC
HEDGECOCK, CJR
[J]. TETRAHEDRON LETTERS, 1993, 34 (01) : 167 - 170
[2] APPLICATION OF THE IBUKA-YAMAMOTO REACTION TO A PROBLEM IN STEREOCHEMICAL COMMUNICATION - A STRATEGY FOR THE STEREOSPECIFIC SYNTHESIS AND STABILIZATION OF THE TRIENE SUBSTRUCTURE OF RAPAMYCIN THROUGH SULFONE SUBSTITUTION
CHEN, SH
HORVATH, RF
JOGLAR, J
FISHER, MJ
DANISHEFSKY, SJ
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1991, 56 (20) : 5834 - 5845
[3] READILY ACCESSIBLE 12-I-5 OXIDANT FOR THE CONVERSION OF PRIMARY AND SECONDARY ALCOHOLS TO ALDEHYDES AND KETONES
DESS, DB
MARTIN, JC
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1983, 48 (22) : 4155 - 4156
[4] NEW PROCEDURE FOR THE DIRECT GENERATION OF TITANIUM ENOLATES - DIASTEREOSELECTIVE BOND CONSTRUCTIONS WITH REPRESENTATIVE ELECTROPHILES
EVANS, DA
URPI, F
SOMERS, TC
CLARK, JS
BILODEAU, MT
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1990, 112 (22) : 8215 - 8216
[5] ENANTIOSELECTIVE ALDOL CONDENSATIONS .3. ERYTHRO-SELECTIVE CONDENSATIONS VIA ZIRCONIUM ENOLATES
EVANS, DA
MCGEE, LR
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1981, 103 (10) : 2876 - 2878
[6] STEREOSELECTIVE ALDOL REACTIONS OF CHLOROTITANIUM ENOLATES - AN EFFICIENT METHOD FOR THE ASSEMBLAGE OF POLYPROPIONATE-RELATED SYNTHONS
EVANS, DA
RIEGER, DL
BILODEAU, MT
URPI, F
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1991, 113 (03) : 1047 - 1049
[7] ON THE CHEMISTRY AND HIGH-FIELD NUCLEAR MAGNETIC-RESONANCE SPECTROSCOPY OF RAPAMYCIN
FINDLAY, JA
RADICS, L
[J]. CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1980, 58 (06): : 579 - 590
[8] ON THE REMARKABLE PROPENSITY FOR CARBON CARBON BOND-CLEAVAGE REACTIONS IN THE C8-C10 REGION OF FK-506
FISHER, MJ
CHOW, K
VILLALOBOS, A
DANISHEFSKY, SJ
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1991, 56 (08) : 2900 - 2907
[9] SYNTHETIC STUDIES TOWARD RAPAMYCIN - A SOLUTION TO A PROBLEM IN CHIRALITY MERGER THROUGH USE OF THE IRELAND REACTION
FISHER, MJ
MYERS, CD
JOGLAR, J
CHEN, SH
DANISHEFSKY, SJ
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1991, 56 (20) : 5826 - 5834
[10] GOULET MT, 1990, TETRAHEDRON LETT, V31, P4845

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