A NOVEL APPLICATION OF THE DESS-MARTIN REAGENT TO THE SYNTHESIS OF AN FK506 ANALOG AND OTHER TRICARBONYL COMPOUNDS

被引：64

作者：

BATCHELOR, MJ ^{[1
]}

GILLESPIE, RJ ^{[1
]}

GOLEC, JMC ^{[1
]}

HEDGECOCK, CJR ^{[1
]}

机构：

[1] ROUSSEL LABS LTD,KINGFISHER DR,SWINDON SN3 5BZ,WILTS,ENGLAND

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 01期

关键词：

D O I：

10.1016/S0040-4039(00)60085-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The use of the Dess-Martin reagent for the oxidation of beta-hydroxy and beta-ketoamides, esters and ketones to the corresponding tricarbonyl compounds is reported. The method is shown to be applicable to the synthesis of analogues of the immunosuppressant FK506.

引用

页码：167 / 170

页数：4

共 19 条

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