OPTIMAL CONDITIONS FOR FRACTIONATION OF RAPESEED LECITHIN WITH ALCOHOLS

被引:59
作者
SOSADA, M
机构
[1] Department of Applied Pharmacy and Drug Technology, Faculty of Pharmacy, Silesian Medical University, Sosnowiec, 41-200
关键词
ALCOHOLS; EXTREME EXPERIMENTS DESIGN; LECITHIN; LECITHIN FRACTIONATION; OPTIMIZATION OF EXTRACTION PROCESS; PHOSPHATIDYLCHOLINE; RAPESEED LECITHIN;
D O I
10.1007/BF02552715
中图分类号
O69 [应用化学];
学科分类号
081704 [应用化学];
摘要
Deoiled rapeseed lecithin was fractionated with ethanol, and optimum conditions have been determined to improve purified lecithin yield and phosphatidylcholine (PC) enrichment. The effect of extraction time, solvent volume, ethanol concentration and temperature on the yield and the PC enrichment have been described in the form of regression equations. A full factorial experiment method and a second-order orthogonal design were used in the study. 'rhe regression equations were calculated for the maximum value of the response functions optimized by an electronic data processing method, and the results (yield and PC enrichment calculated from regression equations) were compared with those obtained in control experiments. The use of calculated optimal parameters in the fractionation process led to 81-96% and 58% increments in yield and PC enrichment, respectively.
引用
收藏
页码:405 / 410
页数:6
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