ACETOGENIC ISOQUINOLINE ALKALOIDS .20. ATROP-DIASTEREOMER SEPARATION BY RACEMATE RESOLUTION TECHNIQUES - N-METHYL-DIONCOPHYLLINE-A AND ITS 7-EPIMER FROM ANCISTROCLADUS-ABBREVIATUS

被引：32

作者：

BRINGMANN, G

LISCH, D

REUSCHER, H

ASSI, LA

GUNTHER, K

机构：

[1] UNIV ABIDJAN,CTR NATL FLORIST CONSERVATOIRE & JARDIN BOT,ABIDJAN 22,COTE IVOIRE

[2] DEGUSSA,FORSCH CHEM,ORGAN & BIOL CHEM,W-6450 HANAU,GERMANY

来源：

PHYTOCHEMISTRY | 1991年 / 30卷 / 04期

关键词：

ANCISTROCLADUS-ABBREVIATUS; ANCISTROCLADACEAE; STEM BARK; NAPHTHYL ISOQUINOLINE ALKALOIDS; N-METHYL-DIONCOPHYLLINE A; CHEMOTAXONOMY;

D O I：

10.1016/S0031-9422(00)95222-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The isolation of N-methyl-dioncophylline A and N-methyl-7-epi-dioncophylline A from Ancistrocladus abbreviatus is described. Atrop-diastereomer resolution was achieved analytically on a chiral chromatographic phase, and preparatively after esterification with a chiral carboxylic acid. Structural elucidation assisted by partial synthesis is reported and chemotaxonomic implications of this first isolation of Dioncophyllaceae alkaloids from an Ancistrocladus species are discussed.

引用

页码：1307 / 1310

页数：4

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