Selected fungi were grown on agar plates in the presence of naringenin, apiforol, apiforol 7-O-rhamnoglucoside, or apigeninidin. Of the four compounds tested, only apigeninidin inhibited the growth of Fusarium oxysporum, Gibberella zeae, Gliocladium roseum, Alternaria solani, and Phytophthora infestans. In contrast, the growth of Rhizoctonia solani, Sclerotium rolfsii, and Rhizopus stolonifer (- and +) was not effected by any compound. Since apigeninidin is present in seeds of Sorghum sp., we hypothesize that apigeninidin may play a role in mold resistance and that apiforol accumulates as a biosynthetic precursor of apigeninidin, not as a fungal defense compound.