ROLE OF HYPOXIC PULMONARY VASOCONSTRICTION IN PULMONARY GAS-EXCHANGE AND BLOOD-FLOW DISTRIBUTION .1. PHYSIOLOGICAL CONCEPTS

被引：90

作者：

MARSHALL, BE ^{[1
]}

MARSHALL, C ^{[1
]}

FRASCH, F ^{[1
]}

HANSON, CW ^{[1
]}

机构：

[1] UNIV PENN,SCH MED,CTR ANESTHESIA RES,PHILADELPHIA,PA 19104

来源：

INTENSIVE CARE MEDICINE | 1994年 / 20卷 / 04期

关键词：

LUNG; VENTILATION PERFUSION; PRESSURE-FLOW; COMPUTER MODEL;

D O I：

10.1007/BF01708968

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

The regulation of the distribution of ventilation/perfusion ratios by hypoxic pulmonary vasoconstriction contributes to both the efficiency of gas exchange and to pulmonary hemodynamics. In this review, the first of a two part series, are summarized the physiologic principles on which the analysis of ventilation/perfusion ratios and of pressure - flow relationships are based. A new combined analysis is introduced that permits the important contributions of hypoxic pulmonary vasoconstriction to overall gas exchange to be demonstrated in the circumstances of clinical complexity.

引用

页码：291 / 297

页数：7

共 30 条

[1] BLUNTED HYPOXIC PULMONARY VASOCONSTRICTION BY INCREASED LUNG VASCULAR PRESSURES [J].

BENUMOF, JL ;

WAHRENBROCK, EA .

JOURNAL OF APPLIED PHYSIOLOGY, 1975, 38 (05) :846-850

[2]

BERGOFSKY EH, 1968, FED PROC, V27, P1420

[3]

BURTON AC, 1972, PHYSL BIOPHYSICS CIR, P71

[4] HYPOXIC PULMONARY VASOCONSTRICTION DOES NOT AFFECT HYDROSTATIC PULMONARY-EDEMA FORMATION [J].

CHENEY, FW ;

BISHOP, MJ ;

EISENSTEIN, BL ;

ARTMAN, LD .

JOURNAL OF APPLIED PHYSIOLOGY, 1987, 62 (02) :776-780

[5] THE EFFECT OF CARDIAC-OUTPUT ON ARTERIAL BLOOD OXYGENATION [J].

CHENEY, FW ;

COLLEY, PS .

ANESTHESIOLOGY, 1980, 52 (06) :496-503

[6]

CUTAIA M, 1990, CHEST, V93, P707

[7] EFFECTS OF VENTILATION-PERFUSION INEQUALITY ON ELIMINATION OF INERT GASES [J].

FARHI, LE ;

YOKOYAMA, T .

RESPIRATION PHYSIOLOGY, 1967, 3 (01) :12-&

[8] A THEORETICAL STUDY OF THE COMPOSITION OF THE ALVEOLAR AIR AT ALTITUDE [J].

FENN, WO ;

RAHN, H ;

OTIS, AB .

AMERICAN JOURNAL OF PHYSIOLOGY, 1946, 146 (05) :637-653

[9]

FUNG YC, 1984, CIRCULATION, P290

[10] BLOOD-FLOW THROUGH VASA VASORUM IN ARTERIES AND VEINS - EFFECTS OF LUMINAL PO2 [J].

HEISTAD, DD ;

ARMSTRONG, ML ;

AMUNDSEN, S .

AMERICAN JOURNAL OF PHYSIOLOGY, 1986, 250 (03) :H434-H442

← 1 2 3 →